Uba3 Polyclonal Antibody for Rat(Rattus norvegicus) | EIAab.comUba3 Polyclonal Antibody for Rat(Rattus norvegicus)

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Uba3 (Gene name),

NEDD8-activating enzyme E1 catalytic subunit (Protein name ), UBA3_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Uba3(Ube1c);

Protein name:

NEDD8-activating enzyme E1 catalytic subunit;

Alternative:

Ubiquitin-activating enzyme E1C;NEDD8-activating enzyme E1C;Ubiquitin-like modifier-activating enzyme 3(Ubiquitin-activating enzyme 3);

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Heterodimer of UBA3 and NAE1. Interacts with NEDD8, UBE2F and UBE2M (By similarity). Binds ESR1 and ESR2 with bound steroid ligand.

Function:

Catalytic subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Down-regulates steroid receptor activity. Necessary for cell cycle progression.

Subcellular Location:

N/A

Protein Attributes:

Sequence length:

462

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

462:

TPQTVLFKLH | FT

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Rn.162761

KEGG:

rno:117553

STRING:

10116.ENSRNOP00000008893

Pfam:

PF08825

SMR:

Q99MI7

String:

Q99MI7

Uniprot:

Q99MI7

FOR

ELISA Kit for Rat NEDD8-activating enzyme E1 catalytic subunit

Cat.:

E1027h

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96T

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ELISA Kit for Rat NEDD8-activating enzyme E1 catalytic subunit

Cat.:

E1027m

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MSDS:

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Packing:

96T

ELISA Kit for Rat NEDD8-activating enzyme E1 catalytic subunit

Cat.:

E1027r

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Packing:

96T

CLIA Kit for Rat NEDD8-activating enzyme E1 catalytic subunit

Cat.:

U1027r

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Packing:

96T

CLIA Kit for Rat NEDD8-activating enzyme E1 catalytic subunit

Cat.:

U1027h

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

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CLIA Kit for Rat NEDD8-activating enzyme E1 catalytic subunit

Cat.:

U1027m

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MSDS:

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Packing:

96T

Polyclonal Antibody for Rat NEDD8-activating enzyme E1 catalytic subunit

Cat.:

P1027Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat NEDD8-activating enzyme E1 catalytic subunit

Cat.:

P1027Rb-r

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat NEDD8-activating enzyme E1 catalytic subunit

Cat.:

P1027Rb-h

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Rat NEDD8-activating enzyme E1 catalytic subunit

Protein for Rat NEDD8-activating enzyme E1 catalytic subunit

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"The activating enzyme of NEDD8 inhibits steroid receptor function."
Fan M. , Long X. , Bailey J.A. , Reed C.A. , Osborne E. , Gize E.A. , Kirk E.A. , Bigsby R.M. , Nephew K.P.
Mol. Endocrinol.16:315-330(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;INTERACTION WITH ESR1 AND ESR2;TISSUE SPECIFICITY
strain: Sprague-Dawley.
tissue: Uterus.
2.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Lung.

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